The smart Trick of Makatussin Syrop That No One is Discussing
The smart Trick of Makatussin Syrop That No One is Discussing
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nitrous oxide and codeine both equally raise sedation. Prevent or Use Alternate Drug. Limit use to patients for whom different therapy choices are inadequate
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chloroquine will boost the stage or impact of codeine by influencing hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Helps prevent conversion of codeine to its Energetic metabolite morphine.
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desipramine decreases effects of codeine by influencing hepatic enzyme CYP2D6 metabolism. Use Caution/Keep an eye on. Stops conversion of codeine to its active metabolite morphine.
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abiraterone will increase amounts of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Warning/Watch. Stay clear of coadministration of abiraterone with substrates of CYP2D6. If different therapy here can't be applied, training warning and consider more info a dose reduction from the CYP2D6 substrate.
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Use is contraindicated in sufferers obtaining monoamine oxidase inhibitors (MAOIs) or in fourteen days of stopping these therapy; MAOIs may well potentiate results of codeine’s Energetic metabolite, which includes respiratory melancholy, coma, and confusion